Alumni

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Former post-docs and research associates

Dr. Akshari GUPTA
PhD, National Institute of Genetics, Japan (12-17)

MRes Structural Biology, Imperial College London, UK (11-12)

BTech Biotechnology, Indian Institute of Technology Madras, India (07-11)

Post-doc 17-18
I am interested in understanding the formation of centriole microtubules from a structural and biochemical perspective.
Dr. Benita WOLF, M.D.  
Post-doc, Inst Mol Biol, Hannover/Tübingen, DE (08-12)
MD thesis, Prof. Weinbrenner, Tech. Uni Dresden, DE (07)
Medicine, Technical Uni Dresden, DE (07)
Post-doc 12-17
I am interested in the molecular basis of asymmetric cell division and its implications for stem cell and cancer stem cell biology.
Alessandro DE SIMONE  
MSc. Physics of Complex Systems, Uni Turin (11) PhD 12-16
Mathematical modeling of centrosome separation in C. elegans early embryo.
I use a combination of experimental, image processing, computational and mathematical approaches aiming at better understanding the mechanisms of centrosome separation.
Dr. Nicola DYNES  
Post-doc, Dr. Costanzo, Cancer Research UK London Research Institute, Clare Hall Laboratories, UK (11-12)
PhD Biochem and Cell Biol, Dr V. Costanzo, CRUK Clare Hall Laboratories, UK (07-11)
MSc Biochemistry, University of Cambridge, UK (07)
Post-doc 12-16
I would like to understand how centrosome proteins work together to build a centriole. How do they function at a molecular level, how are they regulated, and how is procentriole formation restricted to only one position at the base of the mother centriole?
Dr. Virginie HAMEL HACHET  
Staff scientist, EPFL, Lausanne, CH (12-15)
Post-doc, EPFL, Lausanne, CH (05-12)
PhD, EMBL, Heidelberg, DE (04)
SV 1527
[+ 41 21 69] 30710
My work focuses on understanding basic processes underlying cell division, mainly mitotic entry and centrosome duplication.
Dr. Paul GUICHARD  
PhD Cell biol, Dr. Tassin & Marco, Inst Curie, FR  (10)
MSc Biochemistry – University Paris 7 – FR (07)
SV 1527
[+ 41 21 69] 30710
My work focuses on deciphering centriole assembly using biochemistry and cryo-electron tomography. I’m developping Trichonympha as a model organism to study centriole biogenesis.
Dr. Sachin KOTAK  
PhD, J W Goethe Uni, Frankfurt am Main, DE (07)
MSc. Plant Molecular Biol, Uni Dehli, New Dehli, IN (02)
SV 1527
[+ 41 21 69] 30710
I am interested in unravelling the mechanisms of spindle positioning in human cells and in C. elegans embryos. In general, my work aim to decipher the pathway by which spindle positioning is coupled with mitotic progression.
Dr. Meritxell ORPINELL  

Post-doc, Dr. Tora, IGBMC,Strasbourg, FR (07-10)
PhD Biochem, Prof. Zorzano, Uni Barcelona, SP (06)
Internship, Prof. Moysset, Uni Barcelona, SP (98-00)

SV 1527
[+ 41 21 69] 30710

My current work focuses on a proteomic screen directed to identify HsSAS-6-interacting proteins in human cells, with the aim of further deciphering the mechanisms by which this key component ensures procentriole formation.
Dr. Fernando ROMERO BALESTRA  

PhD Biology, Prof. Jimenez, CABD, Seville, SP (09)
MSc.Exp. Biology, Uni Seville, SP (02)
BSc. Biology, Uni Seville, SP (00)

SV 1527
[+ 41 21 69] 30710

I am interested in the mechanisms regulating centriole duplication and the role of centrosomes in the context of asymmetric cell division.
Prof. Daiju KITAGAWA, Associate Professor  
Centrosome Biology Laboratory
Center for Frontier Research
National Institute of Genetics
Mishima, Japan
Post-doc 06-11
Centrosome biogenesis and function are still of my interest. I am aiming for understanding how a lovely, but complex structure “centriole” assembles, somewhere on the country-side in Japan.
Dr. Katayoun AFSHAR, Staff scientist  
CHUV
Lausanne, Switzerland
Research Associate 01-11
Staff Scientist and FAMH Candidate at Centre Hospitalier Universitaire Vaudois – CHUV.
Dr. Tamara MIKELADZE-DVALI, Project/group leader  
Biozentrum der LMU München
Department Biology II
Cell and developmental biology
Planegg-Martinsried, Germany
Post-doc 07-10
The major goal of our research is to understand how centrosomes and in particular centrioles are regulated in different tissues during the development of a multicellular organism.
Dr. Marie DELATTRE, Group leader  
Team ‘Evolution and Plasticity of the Cell Division’
CNRS, Laboratory of Molecular Biology of the Cell
ENS Lyon, France
Post-doc 01-06
We want to decipher the evolutionary dynamics of cellular events. We have chosen the one-cell stage nematode embryo as a model system. Using the diversity of phenotypes found in more than 60 worm species bred in the lab, we study the evolution of mitotic spindle shape, internal microtubule based forces, centrosome origin, etc.
Dr. Jean-Michel BELLANGER, Staff scientist  
Debant lab, INSERM
Macromolecular Biochemistry Research Center
Signaling and cytoskeleton dynamics
Montpellier, France
Post-doc 00-04
In the lab, we are interested in identifying the signal transduction pathways controlling the activity of Rho-GTPases especially in cell motility and neuronal development. In addition, we are interested in understanding how the deregulation of the Rho-GTPase pathways participates to oncogenesis and to neuronal developmental defects.
Dr. Moira COCKELL, Freelance Scientific Editor  
ALWRITE
Scientific writing and editing services
Lausanne, Switzerland
Research Assistant 01-03
Dr Moira Cockell offers a writing and editing service dedicated to helping researchers communicate effectively and efficiently. Her skills as an editor and scientist are helping others to raise the impact of their writing by ensuring that their ideas are expressed with optimum clarity, concision and eloquence. Confidential references are available on request.

Former PhD students

Melina SCHOLZE
MSc. Biosciences, ENS de Lyon, FR (13)

B.Sc. Biology, Pavol Jozef Safari Uni, SK (11)

PhD student 14-18
My work focuses on understanding regulatory mechanisms leading to asymmetric spindle positioning using the early C. elegans embryo as a model system for asymmetric cell division.
Veronika VILLIMOVA
MSc. Biosciences, ENS de Lyon, FR (13)

B.Sc. Biology, Pavol Jozef Safari Uni, SK (11)

PhD student 14-18
My work focuses on revealing the centriolar structure using biochemistry and cry-electron microscopy on Trichonympha centrioles.
Lukas VON TOBEL  
MSc. Biochemistry, ETH Zurich, CH (08) PhD student 11-15
Mechanisms of differential centriole inheritance in the C. elegans germ line.
Using C. elegans as a model system, we try to analyze how centrioles are eliminated during oogenesis and how they are maintained during spermatogenesis.
Dr. Zoltán SPIRÓ , Postdoc  

Winkler  lab. National University of Singapore, Singapore

Summer student 09

PhD student 10-14

I have been interested in exploring different aspects of asymmetric cell division using the 1-cell stage C. elegans embryo as a model system.
Dr. Simon BLANCHOUD , Postdoc  

Wilson lab. University of Otago, New Zealand.

PhD student 08-13

Postdoc 13-14

I studied polarity establishment in the developing C. elegans one-cell stage embryo, combining quantitative data acquisition with mathematical modeling.
Zhou FANG, Law student  

Canada.

PhD student 10-14

I worked on finding new chemical compounds that could be used to study centrosome duplication in human cells.
Dr. Christian GENTILI, Postdoc  
Ferrari lab, Uni Zürich
Institute of Molecular Cancer Research (CH)
PhD student 09-13
Investigating the role of protein tyrosine phosphatases during DNA damage response in human cells. Development of novel inhibitors of CDC25 phosphatases.
Dr. Kalyani THYAGARAJAN  
 Switzerland Post-doc 11-12

PhD student 06-11

Dr. Alexandra BEZLER, Post-doc  
Keller lab, University of Lausanne
Department of Ecology and Evolution
Lausanne, Switzerland
PhD student 07-11
Meiotic drive leads to unequal transmission of chromosomes to the offspring, thus affecting the inheritance of aneuploidies as well as genome defense. Using C. elegans as a model system, I am investigating the underlying mechanisms.
Dr. Petr STRNAD, Post-doc  
Ellenberg lab, EMBL
Cell Biology and Biophysics
Heidelberg
Germany
Post-doc 09-10

PhD student 04-08

PostDoc at EMBL Heidelberg developing new microscopy technology.
Dr. Yemima BUDIRAHARDJA, Post-doc  
Zaidel-Bar lab, RCE Mechanobiology Institute
National University of Singapore
Singapore
Post-doc 08-10

PhD student 04-08

I am studying regulation of cell adhesion during development and I am using C. elegans embryo as a model system to study the process.
Dr. Gregor KOHLMAIER, Senior Medical Communications Manager  
SAN GmbH
Bern
Switzerland
PhD student 05-09
Gregor currently works in Medical Communications (SAN GmbH), bridging the information gap between basic cancer research, drug development and clinical practice. He drives medical education programs in Switzerland and other parts of Europe that help hematologists and oncologists in their clinical decision-making in an increasingly complex treatment landscape.
Dr. Tu NGUYEN-NGOC, M.D. Medical Oncologist  
Lausanne Cancer Center
Medical Oncology
CHUV
Lausanne, Switzerland
PhD student 03-08
 After a few years torturing poor little worms in Pierre’s lab, trying to find THE mechanism governing spindle positioning in asymmetric cell division, which proved to be a very stimulating and rewarding experience, Tu set new challenges by returning to hospital and clinical wards, now curing humans (instead of torturing them?!).
Dr. Sebastian LEIDEL, Group leader  
Max Planck Institute for Molecular Biology
Münster
Germany
PhD student 01-05
All cellular RNA molecules contain chemically modified nucleosides. Even though this phenomenon occurs in all species we know very little about the function of most of these modifications. My lab seeks to unravel this fundamental question of molecular biology in yeast, worms(!), zebrafish and human (stem) cells.
Dr. Remi SONNEVILLE, Post-doc  
Blow lab, Wellcome Trust Centre for Gene Regulation and Expression
College of Life Sciences, University of Dundee
Scotland, UK
Post-doc 05-07

PhD student 01-05

I am currently working on DNA replication in C. elegans.
Dr. Kelly COLOMBO MAURAT, Teacher  
Moudon, VD
Switzerland
PhD student 00-04
Teacher of science and mathematics.

Former lab technicians

Tania Hübscher
BSc Biology, Université Neuchâtel

MSc Life Sciences, EPFL

Technician 17-18
Apart from routine maintenance in the lab, I mainly work on centrosome duplication (Jian Qiu) and centrioles cartwheel assembly (Niccolo Banterle).
Isabelle FLÜCKIGER
Lab techn., Prof Gönczy, EPFL, Lausanne, CH(09-17)                  Lab techn., Addex pharma, Geneva (04-07) Lab techn. CFC, Prof Meda, Uni Geneva, CH(02) Technician 09-17
Apart from routine maintenance of the lab, I mainly work on mitotic entry and centrosome duplication.
Karine BAUMER, Lead lab technician  
Philip Morris International
R&D Genomic Research and Technology Lab
Neuchâtel
Switzerland
Lab techn. 00-05
I was the first lab technician in Pierre’s Lab, setting up the lab with him, and worked at ISREC during 5 years.
My new position is now at Philip Morris International in Neuchâtel, working on cancer research at R&D Genomic Research and Technology Lab, as a Lead Lab Technician.